Platelet Aggregate Filtration Pressure--A Method of Measuring Platelet Aggregation in Whole Blood

Abstract

A method of measuring platelet aggregation in whole blood is described. This method depends upon the filtration characteristics of whole blood after platelet aggregation has been induced in it in a standard fashion. The relationship of the filtration pressure to the final concentration of added ADP, the nature and final concentration of the anticoagulant, amount of agitation, time elapsed after venepuncture, time elapsed after the addition of ADP, platelet count and haematocrit are defined. The advantages of the method are discussed.