The Diffusion Constant of Penicillin
- 5 January 1945
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 101 (2610), 21
- https://doi.org/10.1126/science.101.2610.21
Abstract
The diffusion constant of penicillin was measured with the sintered glass membrane technic over a pH range 4-8 and at 0.5[degree] C. The diffusion constants were found by the equation: D = V2 C2/ tKC1. Penicillin concs. were estimated by turbidimetric microbiol. assay using Staphylococcus aureus as the test organism. Application of the Stokes-Einstein equation relating D to molecular radius showed that at pH 7 the ladius of the penicillin molecule was 5.37 A. The calculated mol. wt. was 490.This publication has 3 references indexed in Scilit:
- Diffusion Velocity and Molecular Weight. I. The Limits of Validity of the Stokes--Einstein Diffusion EquationJournal of the American Chemical Society, 1939
- THE CALIBRATION OF DIFFUSION MEMBRANES AND THE CALCULATION OF MOLECULAR VOLUMES FROM DIFFUSION COEFFICIENTSThe Journal of general physiology, 1937
- Diffusion Coefficients in Alcohol—Water MixturesJournal of the American Chemical Society, 1935