Motor Nerve Conduction Velocity in Experimental Portal-Systemic Shunting

Abstract
The influence of portal-systemic shunting on motor nerve conduction velocity (MCV) was analyzed in rats with portacaval shunts. At 3 and 8 wk after the shunting there was a marked but transient fall in MCV. At 16 wk the MCV had almost normalized, despite substained portal-systemic shunting. The results favor hepatocellular failure as the more important pathophysiological mechanism in hepatic neuropathy.