New synthetic routes to spiroacetals. The 3,4-dihydro-2H-pyran approach to (±)-talaromycin B
- 1 January 1985
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 9,p. 1879-1883
- https://doi.org/10.1039/p19850001879
Abstract
The nucleophilic cleavage of the oxirane (9) by the organocuprate derived from 3-ethyl-6-lithio-3,4-dihydro-2H-pyran (7) was the key step in a synthesis of racemic talaromycin B (12). A similar synthesis of desethyltalaromycin B (15) from (9) and 6-lithio-3,4-dihydro-2H-pyran was achieved.This publication has 1 reference indexed in Scilit:
- NOC approach to spiroketals. A total synthesis of (.+-.)-talaromycin BJournal of the American Chemical Society, 1984