Infectious Mononucleosis with Intense Jaundice of Long Duration

Abstract

JAUNDICE in infectious mononucleosis was first described in 1923 by Downey and McKinlay.¹ Since that time, scattered reports of its occurrence have appeared.^{2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21} Martin,⁸ in 1941, described 13 previously reported cases. In 1944 Boger¹⁷ found 27 cases, and Spring,¹⁴ in the same year, estimated that 35 cases had been recorded. Wechsler²¹ discovered an additional 25 cases and reported 34 cases of his own from an epidemic of infectious mononucleosis. Thus, at least 100 cases have been described. This figure is in no sense an adequate reflection of the frequency of clinical jaundice in infectious mononucleosis, since undoubtedly many cases remain . . .