A New Concept of the Etiology of Megaloureters

Abstract

THE association of megalobladder and megaloureters with megacolon has been reported.^{1 2 3} Twenty-two of our patients with Hirschsprung's disease were studied with cystometrograms; in 12 patients the bladder capacity was considerably above normal. In 7 of these the changes were pronounced, with absence of emptying contractions in response to filling increments. Maximum distention of the bladder produced an urge to void and emptying seemed to take place because of increased intraabdominal pressure following strong voluntary contractions of the abdominal musculature. In addition to these bladder abnormalities, 3 patients with bilateral megaloureters and 1 with a unilateral megaloureter were treated in our . . .