Distribution of sialic acid receptors and influenza A virus of avian and swine origin in experimentally infected pigs
Open Access
- 8 September 2011
- journal article
- Published by Springer Nature in Virology Journal
- Vol. 8 (1), 434
- https://doi.org/10.1186/1743-422x-8-434
Abstract
Pigs are considered susceptible to influenza A virus infections from different host origins because earlier studies have shown that they have receptors for both avian (sialic acid-alpha-2,3-terminal saccharides (SA-alpha-2,3)) and swine/human (SA-alpha-2,6) influenza viruses in the upper respiratory tract. Furthermore, experimental and natural infections in pigs have been reported with influenza A virus from avian and human sources.Keywords
This publication has 47 references indexed in Scilit:
- Replication of avian, human and swine influenza viruses in porcine respiratory explants and association with sialic acid distributionVirology Journal, 2010
- Comparative distribution of human and avian type sialic acid influenza receptors in the pigBMC Veterinary Research, 2010
- Comparative Pathogenesis of an Avian H5N2 and a Swine H1N1 Influenza Virus in PigsPLOS ONE, 2009
- Amino Acid 226 in the Hemagglutinin of H4N6 Influenza Virus Determines Binding Affinity for α2,6-Linked Sialic Acid and Infectivity Levels in Primary Swine and Human Respiratory Epithelial CellsJournal of Virology, 2008
- Sialic acid receptor detection in the human respiratory tract: evidence for widespread distribution of potential binding sites for human and avian influenza virusesRespiratory Research, 2007
- An Avian Influenza H5N1 Virus That Binds to a Human-Type ReceptorJournal of Virology, 2007
- Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptorsNature, 2006
- Pathogenicity of a highly pathogenic avian influenza virus, A/chicken/Yamaguchi/7/04 (H5N1) in different species of birds and mammalsArchiv für die gesamte Virusforschung, 2006
- Risk Factors for Human Infection with Avian Influenza A H5N1, Vietnam, 2004Emerging Infectious Diseases, 2006
- Receptor-binding properties of swine influenza viruses isolated and propagated in MDCK cellsVirus Research, 2005