The microbiological degradation of steroids
- 1 January 1948
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 42 (3), 376-383
- https://doi.org/10.1042/bj0420376
Abstract
The oxidation of steroid ketones, as oxidation products of hydroxysteroids, by Proactinomyces erythropolis [Nocardia e], results in disruption of the molecule. Yields of degradation products were small but,by a continuous culture process described, sufficient individual products were isolated for identification. Two types of oxidation are encountered, ring fission at >CO, and removal of the side chain. A steroid cycle in nature is suggested with the soil microflora providing a disposal mechanism for waste materials.This publication has 5 references indexed in Scilit:
- Microbiological Agencies in the Degradation of Steroids: II. Steroid Utilization by the Microflora of Soils.1947
- Microbiological Agencies in the Degradation of SteroidsJournal of Bacteriology, 1944
- The microbiological degradation of steroidsBiochemical Journal, 1943
- On bacteria decomposing cholesterolAntonie van Leeuwenhoek, 1942
- Colorimetric determination of substances containing the grouping —CH2.CO— in urine extracts as an indication of androgen contentBiochemical Journal, 1938