Life-Threatening Ventricular Arrhythmia (Torsades de Pointes) after Haloperidol Overdose
- 1 January 1991
- journal article
- case report
- Published by SAGE Publications in Human & Experimental Toxicology
- Vol. 10 (1), 59-62
- https://doi.org/10.1177/096032719101000110
Abstract
A 48-year-old woman developed QT prolongation and episodes of life-threatening ventricular tachycardia (torsades de pointes) after intentional overdose of haloperidol and orphenadrine. The arrhythmia did not respond to conventional anti-arrhythmic therapy but was suppressed by atrial overdrive pacing. A literature review identified haloperidol as the most likely cause of the torsades de pointes.Keywords
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