Combined MTOR and autophagy inhibition
Top Cited Papers
Open Access
- 19 May 2014
- journal article
- research article
- Published by Taylor & Francis in Autophagy
- Vol. 10 (8), 1391-1402
- https://doi.org/10.4161/auto.29119
Abstract
The combination of temsirolimus (TEM), an MTOR inhibitor, and hydroxychloroquine (HCQ), an autophagy inhibitor, augments cell death in preclinical models. This phase 1 dose-escalation study evaluat...Keywords
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