Different sequence environments of cysteines and half cystines in proteins Application to predict disulfide forming residues
- 11 May 1992
- journal article
- Published by Wiley in FEBS Letters
- Vol. 302 (2), 117-120
- https://doi.org/10.1016/0014-5793(92)80419-h
Abstract
Protein sequences are often derived by translating genetic information, rather than by classical protein sequencing. At the DNA level cysteines and half cystines are indistinguishable. Here we show that the sequential environments of ‘free’ cysteine and half cystine are different. A possible origin of this difference is discussed and a simple method to predict cysteines and half cystines from the amino acid sequence is also presented.This publication has 12 references indexed in Scilit:
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