• Control of a case of acrodermatitis enteropathica was achieved initially after three months of treatment with diiodohydroxyquin (Diodoquin). Reexacerbation of acrodermatitis enteropathica was noted two months after diiodohydroxyquin was discontinued. Treatment with zinc sulfate was substituted and resulted in dramatic and complete resolution of disease within 48 hours. (Arch Dermatol112:687-689, 1976)