Über das Pyocyanin, den blauen Farbstoff des Bacillus Pyocyaneus. IV. Die Konstitution und Synthese des Pyocyanins.

Abstract

Pyocyanin oxidized in alkaline solution with H2O2 yields [alpha]-oxyphenazin and formic acid, [alpha]-oxyphenazin heated at 100[degree] with CH3 SO4 yields crystals (CHH14N2O5S) which produce pyocyanin when dissolved in H2O and made alkaline. The I methyl derivative of pyocyanin treated with acetic anhydride and H2SO4 yields a 2nd derivative which may be converted to pyocyanin by alkali. This derivative hydrogenated in presence of Pt yields a 3rd derivative that produces pyocyanin when treated with HCl and made alkaline. Pyocyanin hydrogenated in presence of Pt yields a compound of \ the molecular weight of pyocyanin.