Amino Acid Sequences of Glycopeptides Obtained from Basic Proline-Rich Glycoprotein of Human Parotid Saliva
- 1 March 1983
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Biochemistry
- Vol. 93 (3), 857-863
- https://doi.org/10.1093/jb/93.3.857
Abstract
A proline-rich glycoprotein, in which proline, glutamic acid, and glycine represent about 80 per cent of the total residues, was obtained from human parotid saliva. The amino acid sequences of glycopeptides obtained from digests of the glycoprotein with clostripain were determined to be Pro-Gly-Lys-Pro-Glu-Gly-Pro-Pro-Pro-Gln-Gly-Gly-Asn(CHO)-Gln-Ser-Gln-Gly-Pro-Pro-Pro-Arg and Pro-Pro-Gln-Gly-Gly Asn(CHO)-Gln-Ser-Gln-Gly-Pro-Pro-Pro-His-Pro-Gly-Lys-Pro-Glu-Arg. The structural relationship between the glycopeptides and the known salivary peptide is discussed.Keywords
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