Isolation and characterization of DNA probes from the short arm of the human X chromosome that detect restriction fragment length polymorphisms
- 1 February 1987
- journal article
- research article
- Published by Canadian Science Publishing in Genome
- Vol. 29 (1), 201-205
- https://doi.org/10.1139/g87-034
Abstract
We have isolated 30 X chromosome specific probes from a flow-sorted library enriched for the human X chromosome. Hybridization to somatic cell hybrids containing different regions of the X chromosome localized nine of these probes to Xp. After testing 185 probe–enzyme combinations, three of the Xp probes were found to detect restriction fragment length polymorphisms. Key words: DNA probe, polymorphisms (restriction), X chromosome.This publication has 7 references indexed in Scilit:
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