Base-sequence-dependent sliding of proteins on DNA
- 6 October 2004
- journal article
- research article
- Published by American Physical Society (APS) in Physical Review E
- Vol. 70 (4), 041901
- https://doi.org/10.1103/physreve.70.041901
Abstract
The possibility that the sliding motion of proteins on DNA is influenced by the base sequence through a base pair reading interaction, is considered. Referring to the case of the T7 RNA-polymerase, we show that the protein should follow a noise-influenced sequence-dependent motion which deviate from the standard random walk usually assumed. The general validity and the implications of the results are discussed.Comment: 12 pages, 3 figureKeywords
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