Abstract
The sympathin stores are relatively resistant to exhaustion. The probability of sympathin being exhausted by the normal body functions is extremely slight. There is usually no appreciable difference in the amount of sympathin which can be produced from a single visceral organ, bilaterally innervated, when one or the other splanchnic nerve is stimulated singly. Under suitable conditions, exhaustion of the sympathin stores by stimulating one splanchnic nerve does not affect the output obtainable from the other. The evidence suggests that little or no duplication of innervation occurs in the sympathetic nervous system. The adrenal medulla is equally resistant to exhaustion of adrenine1.

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