Phosphorylative Inactivation of Aminoglycosidic Antibiotics by Escherichia coli Carrying R Factor

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Abstract
Kanamycin and paromamine are inactivated by an enzyme solution prepared from Escherichia coli carrying R factor; and the 3-hydroxyl group of 6-amino-6-deoxy-D-glucose moiety of kanamycin or the 3-h...