Tissue reaction to alumina implants inserted into the tibiae of rats
- 1 April 1993
- journal article
- research article
- Published by Wiley in Journal of Biomedical Materials Research
- Vol. 27 (4), 421-428
- https://doi.org/10.1002/jbm.820270402
Abstract
We examined the tissue reaction to three alumina implants—single‐crystal alumina (SA), dense polycrystal alumina (DPA), and porous polycrystal alumina (PPA)—inserted transcortically, extending into the medullary canal of rat tibiae, and assessed the quantitative differences in bone reaction using an image processing system. There was no difference in the degree of maturation of newly formed bone around the three kinds of alumina. SA and DPA were encapsulated with a continuous bone layer, but some bone tissue was attached focally around PPA. Bone trabeculae in the control site diminished in size and number chronologically. Multinucleated giant cells were observed on the surface of DPA and PPA, but not on SA. Tabulation of the quantitative evaluation indicated that SA showed the highest, DPA a lower, and PPA the lowest in bone contact rate, bone contact thickness, and bone contact area. These data suggest that SA is superior to the other two as an implant material. © 1993 John Wiley & Sons, Inc.Keywords
This publication has 9 references indexed in Scilit:
- Porous alumina for free-standing implants. Part I: Implant design and in vivo animal studiesThe Journal of Prosthetic Dentistry, 1988
- Single-crystal sapphire endosseous dental implant loaded with functional stress?clinical and histological evaluation of peri-implant tissuesJournal of Oral Rehabilitation, 1988
- Quantitative characterization of cells at the interface of long‐term implants of selected polymersJournal of Biomedical Materials Research, 1986
- Initial bone-implant interfaces of submergible and supramergible endosseous single-crystal sapphire implantsThe Journal of Prosthetic Dentistry, 1986
- Tissue reaction to implanted biomaterialsThe Journal of Prosthetic Dentistry, 1985
- Some aspects of macrophage behavior at the implant interfaceJournal of Biomedical Materials Research, 1984
- The single-crystal sapphire endosteal dental implant: Material characteristics and 18-month experimental animal trialsThe Journal of Prosthetic Dentistry, 1982
- Single crystal alumina for dental implants and bone screwsJournal of Biomedical Materials Research, 1980
- Biological activity and histocompatibility of dense Al2 O3/MgO ceramic implants in ratsJournal of Biomedical Materials Research, 1973