Determinants of intramyocardial pressure in the cat

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Abstract
Determinants of intramyocardial pressure in the cat were investigated by means of a small latex tube inserted into the wall of the left ventricle. Maximal intramyocardial pressures were generally below carotid systolic pressures. Rhythmic variations in intramyocardial pressure occurred and were related to pulmonary ventilation. There was no evidence of efferent vagal activity on the left ventricle. Sympathetic stimulation increased and sympathetic blockade (with Pronethalol) decreased intramyocardial pressure. Intramyocardial pressure was increased by venous infusions and by constriction of the aorta.