Nachweis verschiedener antigener Determinanten vom interspecies Typ in RNS-Tumorviren (C-Typ) der Säuger / Evidence for the Existence of Different Antigenic Determinants of the Interspecies Type in Mammalian RNA-C -Type Tumor Viruses

Abstract

In C-type particles of mammalian origin, two different antigenic determinants of the interspecies type have been revealed by a comparative study of murine-, feline-, suidian-, simian (woolly monkey) (SSV-1)-and RD₁₁₄-viruses. With respect to the distribution of interspecies determinants, these viruses can be arranged into two distinct groups; one comprises the rodent- and cat-, the other the pig- and monkey-viruses. RD₁₁₄-virus appears to share a certain non-interspecies antigenic component with cat viruses (strains Rickard and Gardner) but behaves, as far as its interspecies antigenic determinant is concerned, more similar to pig- and woolly monkey-viruses. In showing the serological differences mentioned, IgG antibody could replace whole serum.