Immunobiology of primary intracranial tumors
- 1 April 1977
- journal article
- research article
- Published by Journal of Neurosurgery Publishing Group (JNSPG) in Journal of Neurosurgery
- Vol. 46 (4), 467-476
- https://doi.org/10.3171/jns.1977.46.4.0467
Abstract
✓ Cellular and humoral immune parameters were evaluated in a series of braintumor patients, 42 with glioblastoma multiforme, 17 with other anaplastic gliomas, and 17 with meningiomas. A degree of anergy was found, which seems in the group as a whole to be proportional to the degree of anaplasia. In addition, serial bimonthly testing in individual cases revealed further reduction in certain immune responses coincident with clinical decline.Keywords
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