Chromosome-Encoded CTX-M-3 from Kluyvera ascorbata : a Possible Origin of Plasmid-Borne CTX-M-1-Derived Cefotaximases

Abstract
A gene identical to plasmid-borne bla CTX-M-3 is present in the chromosome of one Kluyvera ascorbata strain. It is associated with a structure including an inverted repeat right and an open reading frame 477-like gene probably involved in the mobilization of bla CTX-M-3 . Two other K. ascorbata strains rendered the previously described bla KLUA-9 gene.