Mechanism of liquefaction of the human ejaculate II. Role of collagenase-like peptidase and seminal proteinase

Abstract

Collagenase-like peptidase and seminal proteinase were isolated from human testis and human seminal plasma. The effects of both enzymes on proteins isolated from the human ejaculate were studied. Both enzymes degraded ejaculate proteins. Collagenase-like peptidase is evidently responsible for the 1st, and seminal proteinase for the 2nd, phase of human ejaculate liquefaction in vitro.