Production of antibodies against influenza virus by somatic cell hybrids between mouse myeloma and primed spleen cells.
- 1 July 1977
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 74 (7), 2985-2988
- https://doi.org/10.1073/pnas.74.7.2985
Abstract
Somatic cell hybrids were produced between mouse myeloma cells and spleen cells derived from a BALB/c mouse immunized with purified influenza virus. The hybrid cells produced large amounts of antibodies specific for the hemagglutinin of the virus and were able to induce tumor formation when injected into BALB/c mice.This publication has 16 references indexed in Scilit:
- Persistence of virus-specific memory B cells in mice CNSNature, 1977
- The analysis of the monoclonal immune response to influenza virus. II. The antigenicity of the viral hemagglutinin.The Journal of Experimental Medicine, 1976
- Somatic cell hybridization of mouse myeloma cellsCell, 1976
- Derivation of specific antibody‐producing tissue culture and tumor lines by cell fusionEuropean Journal of Immunology, 1976
- The analysis of the monoclonal immune response to influenza virus. I. Production of monoclonal anti‐viral antibodies in vitroEuropean Journal of Immunology, 1975
- Continuous cultures of fused cells secreting antibody of predefined specificityNature, 1975
- Unidirectional loss of human chromosomes in rat-human hybridsExperimental Cell Research, 1973
- A RAPID BANDING TECHNIQUE FOR HUMAN CHROMOSOMESThe Lancet, 1971
- DISQUISITIONS ON ORIGINAL ANTIGENIC SINThe Journal of Experimental Medicine, 1966
- Selection of Hybrids from Matings of Fibroblasts in vitro and Their Presumed RecombinantsScience, 1964