Role of Lymph Nodes in Adjuvant-Induced Arthritis in Rats
Open Access
- 1 September 1964
- journal article
- research article
- Published by BMJ in Annals Of The Rheumatic Diseases
- Vol. 23 (5), 392-396
- https://doi.org/10.1136/ard.23.5.392
Abstract
Secondary lesions do not develop in rats if all the draining lymph nodes are removed within 5 days of injecting adjuvant into the foot-pad or flank. If the nodes are removed on day 7, the development of secondary lesions is not impaired. Draining lymph nodes increase in weight most rapidly during the first 5 to 7 days after injection.This publication has 6 references indexed in Scilit:
- CHEMOTHERAPY OF ARTHRITIS INDUCED IN RATS BY MYCOBACTERIAL ADJUVANTBritish Journal of Pharmacology and Chemotherapy, 1963
- Studies on adjuvant‐induced polyarthritis in rats. II. Histogenesis of joint and visceral lesionsArthritis & Rheumatism, 1963
- Passive Transfer of Adjuvant Arthritis in Rats with Living Lymphoid Cells of Sensitized DonorsInternational Archives of Allergy and Immunology, 1963
- Studies on adjuvant‐induced polyarthritis in rats. I. Adjuvant composition, route of injection, and removal of depot siteArthritis & Rheumatism, 1962
- STUDIES OF ARTHRITIS AND OTHER LESIONS INDUCED IN RATS BY INJECTION OF MYCOBACTERIAL ADJUVANT .2. EVIDENCE THAT THE DISEASE IS A DISSEMINATED IMMUNOLOGIC RESPONSE TO EXOGENOUS ANTIGEN1960
- Development of Arthritis, Periarthritis and Periostitis in Rats Given Adjuvants.Experimental Biology and Medicine, 1956