Significance of 7S and Macroglobulin Brucella Agglutinins in Human Brucellosis

Abstract

A DEFINITIVE diagnosis of acute human brucellosis is not difficult to pursue in the patients with a history of exposure to the disease and a characteristic course. Considerable difficulty is encountered, however, in two general groups. The first comprises the patients who have had an acute attack, who have been properly treated and yet who have persistent complaints, with a low serum brucella agglutination titer not exceeding 1:80. Up to 30 per cent of presumably recovered patients fall into this category.¹ The second is a smaller group of patients who have been chronically ill but who likewise have low titers . . .