Preparation and spectroscopic properties of some new asymmetric organosilanes

Abstract

Partial reduction of a number of racemic methoxysilanes by a chiral reducing complex of lithium aluminium hydride and a terpene alcohol or alkaloidal alcohol has been used to achieve a kinetic resolution. By this means several new optically active silanes and methoxysilanes have been prepared. Indications have been obtained that the stereochemistry of some reactions reported may differ from that of similar reactions recorded in the literature. The o.r.d. and c.d. spectra of the compounds prepared have been recorded, and the potential value of high-resolution n.m.r. spectroscopy in configurational studies on chiral organosilanes has been demonstrated.