Unprecedented carbon dioxide effect on a Pd-catalysed oxidative carbonylation reaction: a new synthesis of pyrrole-2-acetic esters

Abstract

It has been found that carbon dioxide effectively promotes the Pd-catalysed oxidative cyclisation–alkoxycarbonylation of (Z)-(2-en-4-ynyl)amines 1 leading to pyrrol-2-acetic esters 2.