STUDIES OF THE CARRIER STATE FOLLOWING INFECTION WITH GROUP A STREPTOCOCCI. II. INFECTIVITY OF STREPTOCOCCI ISOLATED DURING ACUTE PHARYNGITIS AND DURING THE CARRIER STATE*

Abstract

Strains of group A, type 14 streptococci isolated from a patient with acute pharyngitis during the acute illness and later during the carrier state caused infections in monkeys inoculated intranasally. Monkeys inoculated with a non-M variant of type 14, isolated during the 20th week, were not infected with this organism, In 3 of the 5 monkeys inoculated with the non-M protein variant, the streptococci subsequently isolated from the pharynx were type 14.