THE AGGLUTINATING AND SENSITIZING CAPACITY OF ANTISERA TO SHEEP RED CELLS AFTER VARYING DEGREES OF PHOTO-OXIDATION

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Abstract
The antiglobulin sensitization test was found to be effective in detecting the sensitizing capacity of sheep cell antibodies which were rendered nonagglutinating by the photo-oxidation process. Such treated antibodies evidently still retain globulin specificity. Non-agglutinating rabbit antibodies to sheep cells may be conjugated with a foreign protein such as egg albumin. A sheep cell-egg albumin unit may then be formed by which it is possible to detect serologically complete or incomplete antibodies to egg albumin in sera of man or animals other than the rabbit.