Hyperthermic isolated perfusion with melphalan in the treatment of advanced malignant melanoma of the lower limb
- 1 July 1990
- journal article
- Published by Oxford University Press (OUP) in British Journal of Surgery
- Vol. 77 (7), 765-767
- https://doi.org/10.1002/bjs.1800770716
Abstract
A retrospective study of 91 patients with malignant melanoma treated by lower limb isolated hyperthermic regional perfusion was performed. Objective response in patients with evaluable disease was 78 per cent. The role of perfusion as primary treatment of large melanomas of the foot is confirmed and recommended. Control of locoregional disease and limb salvage remains a valuable and attainable therapeutic goal using this technique.Keywords
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