THE STRUCTURE OF SOME REACTION PRODUCTS OF THE ACIDIC URINARY METABOLITES OF PROGESTERONE
- 1 February 1968
- journal article
- research article
- Published by Bioscientifica in Journal of Endocrinology
- Vol. 40 (2), 153-163
- https://doi.org/10.1677/joe.0.0400153
Abstract
SUMMARY: After injection of [4-14C]progesterone into rabbits, 62% of the radioactivity recovered from the urine after hydrolysis is extractable from ether into sodium bicarbonate solution. Treatment of these acidic metabolites with potassium borohydride, followed by sodium bismuthate, yields neutral material which can be separated into three zones by thin-layer chromatography. The most polar zone, accounting for 61% of the radioactivity recovered from the plate, consists of epimers of 3,6-dihydroxyandrostan17-al.This publication has 8 references indexed in Scilit:
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