Biochemical aspects of motor neurone disease--Madras pattern
- 1 October 1973
- journal article
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 36 (5), 753-756
- https://doi.org/10.1136/jnnp.36.5.753
Abstract
A detailed study of four cases of MND-Madras has shown a significantly low plasma citrate level in these subjects. Comparison with other related groups of neurological disorders indicates the citrate/pyruvate ratio to be of diagnostic value in MND-Madras. This seems to suggest that the pathophysiology of MND-Madras may centre round altered citrate metabolism.Keywords
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