Distribution of binding sites for 125I-labeled alpha-bungarotoxin in normal and deafferented antennal lobes of Manduca sexta.
- 1 January 1979
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 76 (1), 499-503
- https://doi.org/10.1073/pnas.76.1.499
Abstract
125I-Labeled .alpha.-bungarotoxin was used to determine the distribution of putative acetylcholine receptors in normal and chronically deafferented antennal lobes in the brain of the moth M. sexta. Toxin-binding sites were confined to synaptic regions in the neuropil of normal lobes and to rudiments of these regions in deafferented lobes. Receptors apparently can develop in the insect CNS independently of normal synaptic influences.This publication has 34 references indexed in Scilit:
- Demonstration of an α‐bungarotoxin‐binding nicotinic receptor in fliesFEBS Letters, 1977
- Differentiation of insect sensory neurons in the absence of their normal synaptic targetsDevelopmental Biology, 1976
- Acetylcholine and its metabolic enzymes in developing antennae of the moth, Manduca sextaDevelopmental Biology, 1976
- ACETYLCHOLINE RECEPTORS: NUMBER and DISTRIBUTION IN INTACT and DEAFFERENTED SUPERIOR CERVICAL GANGLION OF THE RAT1Journal of Neurochemistry, 1976
- The distribution of acetylcholine sensitivity over uninnervated and innervated muscle fibers grown in cell cultureDevelopmental Biology, 1973
- Release of Neurotransmitters and Their Interaction with ReceptorsAnnual Review of Biochemistry, 1972
- Innervation and acetylcholine sensitivity of skeletal muscle cells differentiatedin vitrofrom chick embryoJournal of Cellular Physiology, 1971
- Physiological Studies During Formation and Development of Rat Neuromuscular Junctions in Tissue CultureThe Journal of general physiology, 1971
- Development of acetylcholine sensitivity during myogenesisDevelopmental Biology, 1971
- The cholinergic nature of the cercal nerve‐giant fiber synapse in the sixth abdominal ganglion of the American cockroach, Periplaneta americana (L.)Journal of Neurobiology, 1971