Detectable SARS‐CoV‐2 viral RNA in feces of three children during recovery period of COVID‐19 pneumonia
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Open Access
- 29 March 2020
- journal article
- research article
- Published by Wiley in Journal of Medical Virology
- Vol. 92 (7), 909-914
- https://doi.org/10.1002/jmv.25795
Abstract
Coronavirus Disease 2019 (COVID‐19) is a newly emerging infectious disease caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). After its first occurrence in Wuhan of China from December 2019, COVID‐19 rapidly spread around the world. According to the World Health Organization (WHO) statement on March 13, 2020, there had been over 132,500 confirmed cases globally. Nevertheless, the case reports of children are rare, which result in the lack of evidence for preventing and controlling of children's infection. Here, we report 3 cases of SARS‐CoV‐2 infected children diagnosed from February 3 to February 17, 2020 in Tianjin, China. All of these three cases experienced mild illness and recovered soon after treatment, with the nucleic acid of throat swab turning negative within 14, 11, 7 days after diagnosis respectively. However, after been discharged, all the three cases were tested SARS‐CoV‐2 positive in the stool samples within 10 days, in spite of their remained negative nucleic acid in throat swab specimens. Therefore, it is necessary to be aware of the possibility of fecal‐oral transmission of SARS‐CoV‐2 infection, especially for children cases.Keywords
Funding Information
- Program of Tianjin Science and Technology Plan (18ZXDBSY00170)
This publication has 14 references indexed in Scilit:
- Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected PneumoniaNew England Journal of Medicine, 2020
- Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, ChinaJAMA, 2020
- First Case of 2019 Novel Coronavirus in the United StatesNew England Journal of Medicine, 2020
- A Case Series of Children With 2019 Novel Coronavirus Infection: Clinical and Epidemiological FeaturesClinical Infectious Diseases, 2020
- A Novel Coronavirus from Patients with Pneumonia in China, 2019New England Journal of Medicine, 2020
- A Novel Coronavirus Emerging in China — Key Questions for Impact AssessmentNew England Journal of Medicine, 2020
- Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan, ChinaEuropean Radiology, 2020
- [Frist case of severe childhood novel coronavirus pneumonia in China].2020
- Diagnosis and treatment recommendations for pediatric respiratory infection caused by the 2019 novel coronavirusWorld Journal of Pediatrics, 2020
- A novel coronavirus outbreak of global health concernThe Lancet, 2020