• 1 January 1978
    • journal article
    • research article
    • Vol. 15 (5), 392-394
Abstract
Castrate male Sprague-Dawley rats were treated with either testosterone; testosterone and estradiol; testosterone, estradiol and CB-154, an inhibitor of prolactin secretion; or testosterone and CB-154. Estradiol potentiated testosterone-induced growth of the dorsal, lateral and ventral prostate and this effect was not counteracted by CB-154. Estradiol only induced hypertrophy of the dorsal and ventral prostate. Hyperplastic changes occurred in the lateral prostate.