EFFECTS OF ENFLURANE ANAESTHESIA AND SURGERY ON ENDOCRINE FUNCTION IN MAN
- 1 February 1979
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 51 (2), 141-148
- https://doi.org/10.1093/bja/51.2.141
Abstract
Patients (45) underwent enflurane anesthesia and surgery. Anesthesia alone evoked little change in the plasma concentrations of ACTH, cortisol or antidiuretic hormone (ADH), but there were significant increases during surgery. The plasma concentrations of aldosterone increased during anesthesia alone, and a further increase was noted during surgery. Neither enflurane anesthesia nor surgery significantly influenced plasma concentrations of renin activity and thyroxine. A significant decrease in the plasma triiodothyronine concentrations was detected during anesthesia alone, and a further decrease was found during and following surgery. Enflurane anesthesia did not effect the plasma concentration of luteinizing hormone (LH) in male subjects throughout surgery, but a significant decrease in female patients was detected by the 1st day after operation. The plasma concentrations of testosterone decreased during anesthesia alone and surgery, and a further decrease was noted on the 1st day after operation.This publication has 5 references indexed in Scilit:
- EFFECTS OF MORPHINE AND KETAMINE ANAESTHESIA AND SURGERY ON PLASMA CONCENTRATIONS OF LUTEINIZING HORMONE, TESTOSTERONE AND CORTISOL IN MANBritish Journal of Anaesthesia, 1977
- RAPID DECREASE IN PLASMA-TRIIODOTHYRONINE DURING SURGERY AND EPIDURAL ANALGESIA INDEPENDENT OF AFFERENT NEUROGENIC STIMULI AND OF CORTISOLThe Lancet, 1976
- Plasma Levels of ACTH and Cortisol in Man during Diethyl Ether Anesthesia and SurgeryAnesthesiology, 1968
- Clinical and Laboratory Evaluation of a New Inhalation Agent: Compound 347 (CHF2-O-CF2-CHF Cl)Anesthesiology, 1968
- Radioimmunoassay: A Method for Human Chorionic Gonadotropin and Human Luteinizing Hormone1Endocrinology, 1966