Baseline Susceptibility of Primary Human Immunodeficiency Virus Type 1 to Entry Inhibitors
Open Access
- 15 January 2003
- journal article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 77 (2), 1610-1613
- https://doi.org/10.1128/jvi.77.2.1610-1613.2003
Abstract
Human immunodeficiency virus type 1 plasma viruses from 29 entry inhibitor-naive patients were characterized for their susceptibilities to T-20, AMD3100, and RANTES. A strikingly wide range of susceptibilities to T-20 was observed that was influenced by coreceptor usage but not by the susceptibilities of the viruses to inhibitors that target the chemokine receptors or by polymorphisms in the gp41 N helix.Keywords
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