In Vitro Activity of Fosfomycin against Extended-Spectrum-β-Lactamase- Producing Escherichia coli and Klebsiella pneumoniae : Comparison of Susceptibility Testing Procedures
Open Access
- 1 January 2006
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 50 (1), 368-370
- https://doi.org/10.1128/aac.50.1.368-370.2006
Abstract
The agar dilution, broth microdilution, and disk diffusion methods were compared to determine the in vitro susceptibility of 428 extended-spectrum-β-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae to fosfomycin. Fosfomycin showed very high activity against all ESBL-producing strains. Excellent agreement between the three susceptibility methods was found for E. coli , whereas marked discrepancies were observed for K. pneumoniae .Keywords
This publication has 13 references indexed in Scilit:
- High Levels of Antimicrobial Coresistance among Extended-Spectrum-β-Lactamase-Producing EnterobacteriaceaeAntimicrobial Agents and Chemotherapy, 2005
- Etiología y sensibilidad a los antimicrobianos de los uropatógenos causantes de la infección urinaria baja adquirida en la comunidad. Estudio nacional multicéntricoEnfermedades Infecciosas y Microbiología Clínica, 2005
- Epidemiology and Clinical Features of Infections Caused by Extended-Spectrum Beta-Lactamase-Producing Escherichia coli in Nonhospitalized PatientsJournal of Clinical Microbiology, 2004
- In vitro activity of fosfomycin against Gram-negative urinary pathogens and the biological cost of fosfomycin resistanceInternational Journal of Antimicrobial Agents, 2003
- Why fosfomycin trometamol as first line therapy for uncomplicated UTI?International Journal of Antimicrobial Agents, 2003
- Escherichia coli y Klebsiella pneumoniae productores de betalactamasas de espectro extendido en hospitales españoles (Proyecto GEIH-BLEE 2000)Enfermedades Infecciosas y Microbiología Clínica, 2003
- Identification and Broad Dissemination of the CTX-M-14 β-Lactamase in Different Escherichia coli Strains in the Northwest Area of SpainJournal of Clinical Microbiology, 2002
- Epidemiology of Ciprofloxacin Resistance and Its Relationship to Extended-Spectrum -Lactamase Production in Klebsiella pneumoniae Isolates Causing BacteremiaClinical Infectious Diseases, 2000
- Fosfomycin tromethamine susceptibility of outpatient urine isolates of Escherichia coli and Enterococcus faecalisfrom ten North American medical centres by three methodsJournal of Antimicrobial Chemotherapy, 1999
- In vitro susceptibility testing procedures for fosfomycin tromethamineAntimicrobial Agents and Chemotherapy, 1991