The catalysis of nucleotide polymerization by compounds of divalent lead
- 1 December 1979
- journal article
- Published by Springer Nature in Journal of Molecular Evolution
- Vol. 12 (4), 357-364
- https://doi.org/10.1007/bf01732030
Abstract
Soluble lead salts and a number of lead-containing minerals catalyze the formation of oligonucleotides from nucleoside 5′-phosphorimidazolides. The effectiveness of lead compounds correlates strongly with their solubility. Under optimal conditions we were able to obtain 18% of pentamer and higher oligomers from ImpA. Reactions involving ImpU gave smaller yields.Keywords
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