The rate constant for ATP hydrolysis by polymerized actin

Abstract

Polymerized actin hydrolyzes bound ATP in a reaction that depends on the concentration of polymerized ATP‐actin, not on the rate of incorporation of ATP‐actin into the polymer. The apparent first order rate constant is about 0.07 s⁻¹ at 21°C in 50 mM KCl with 1 mM MgCl₂ or CaCl₂.