Palladium(II)-Mediated Cascade Carbonylative Annulation of o-Alkynyl-phenols on Silyl Linker-Based Macrobeads: A Combinatorial Synthesis of a 2,3-Disubstituted Benzo[b]furan Library
- 22 June 2002
- journal article
- letter
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 4 (15), 2607-2609
- https://doi.org/10.1021/ol020111y
Abstract
A palladium(II)-mediated cascade carbonylative annulation of o-alkynylphenols was achieved successfully on silyl linker-based macrobeads, which led to an efficient combinatorial synthesis of a 2,3-disubstituted benzo[b]furan library.Keywords
This publication has 11 references indexed in Scilit:
- An Alkylsilyl-Tethered, High-Capacity Solid Support Amenable to Diversity-Oriented Synthesis for One-Bead, One-Stock Solution Chemical GeneticsJournal of Combinatorial Chemistry, 2001
- Split−Pool Synthesis of 1,3-Dioxanes Leading to Arrayed Stock Solutions of Single Compounds Sufficient for Multiple Phenotypic and Protein-Binding AssaysJournal of the American Chemical Society, 2001
- Carbon−Carbon Bond-Forming Solid-Phase Reactions. Part IIChemical Reviews, 2000
- Synthesis of C(3) Benzofuran-Derived Bisaryl Quaternary Centers: Approaches to Diazonamide AOrganic Letters, 2000
- Hydrogen-Atom Abstraction/Cyclization in Synthesis. Direct Syntheses of Coumestan and CoumestrolThe Journal of Organic Chemistry, 2000
- Dissecting cellular processes using small molecules: identification of colchicine-like, taxol-like and other small molecules that perturb mitosisChemistry & Biology, 2000
- Carbon−Carbon Bond Forming Solid-Phase ReactionsChemical Reviews, 1999
- Isolation and structure determination of diazonamides A and B, unusual cytotoxic metabolites from the marine ascidian Diazona chinensisJournal of the American Chemical Society, 1991
- Palladium catalysed oxidation of primary and secondary alcohols under solid-liquid phase transfer conditionsTetrahedron Letters, 1985
- Noble metal catalysis. III. Preparation of dialkyl oxalates by oxidative carbonylationThe Journal of Organic Chemistry, 1974