A MEDICATION MONITOR AND FLUORESCEIN TECHNIQUE DESIGNED TO STUDY MEDICATION BEHAVIOUR

Abstract
Methods were developed to study medication behavior to obtain accurate and detailed information on the patterns of drug-taking in medication with eye drops. A medication monitor was designed, which recorded the date and hour each time the medication bottle was opened. A fluorescein technique was designed to study the ability of patients to administer the eye drops into the conjunctival sac. Some problems in the measurement of medication behavior are discussed. In a group of patients with open-angle glaucoma, for whom pilocarpine eye drops 3 times daily were prescribed, 18% of dose intervals had a duration of 12 h or more and 11% had a duration of 4 h or less. Fluorescein tests indicated that the patients were usually able to administer the eye drops correctly.