Liver membrane antibodies in alcoholic liver disease: 1. prevalence and immunoglobulin class.
Open Access
- 1 March 1982
- Vol. 23 (3), 221-225
- https://doi.org/10.1136/gut.23.3.221
Abstract
Using an indirect immunofluorescence technique liver membrane antibodies of IgG and IgA class have been demonstrated in a statistically significant proportion of sera from patients with alcoholic hepatitis and alcoholic cirrhosis. IgG and IgA class antibodies were found respectively in 23 and 25% of 48 patients with alcoholic hepatitis, in 27 and 33% of 84 with active cirrhosis, and 67 and 58% of 12 with inactive cirrhosis. These results provide evidence of a humoral immune response in alcoholic liver disease which is directed against, as yet undefined, liver-cell membrane antigens.This publication has 27 references indexed in Scilit:
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