Modulation of Nuclear Factor-κB Activity by Indomethacin Influences Aβ Levels but Not Aβ Precursor Protein Metabolism in a Model of Alzheimer's Disease
- 1 December 2004
- journal article
- research article
- Published by Elsevier in The American Journal of Pathology
- Vol. 165 (6), 2197-2206
- https://doi.org/10.1016/s0002-9440(10)63269-5
Abstract
No abstract availableKeywords
Funding Information
- Coins for Alzheimer's Research Trust (AG-22512, AG-11542, IIRG-02-4010)
- National Institutes of Health (AG-22512, AG-11542, IIRG-02-4010)
- Alzheimer's Association (AG-22512, AG-11542, IIRG-02-4010)
This publication has 43 references indexed in Scilit:
- Nonsteroidal Anti-Inflammatory Drugs Can Lower Amyloidogenic Aß 42 by Inhibiting RhoScience, 2003
- Transforming Growth Factor-β1 Potentiates Amyloid-β Generation in Astrocytes and in Transgenic MiceJournal of Biological Chemistry, 2003
- Secretion and Intracellular Generation of Truncated Aβ in β-Site Amyloid-β Precursor Protein-cleaving Enzyme Expressing Human NeuronsPublished by Elsevier ,2003
- Presenilins are not required for Aβ42 production in the early secretory pathwayNature Neuroscience, 2002
- A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activityNature, 2001
- Enhanced expression of I-κB with neurofibrillary pathology in Alzheimer's diseaseNeuroReport, 2001
- Cyclooxygenases: Structural, Cellular, and Molecular BiologyAnnual Review of Biochemistry, 2000
- PDZ Domain-dependent Suppression of NF-κB/p65-induced Aβ42 Production by a Neuron-specific X11-like ProteinPublished by Elsevier ,2000
- Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic MiceScience, 1996
- Effects of nonsteroidal antiinflammatory drugs on oxidative pathways in A/J miceFree Radical Biology & Medicine, 1995