Perlèche was first described by Lemaistre,1who considered an organism which he calledStreptococcus plicatilisas responsible for the disorder. His clinical and bacteriologic observations were based on a study of 300 cases. The disease had been recognized in various European countries for a long time prior to his work, and had received numerous popular and scientific names, among the latter, angulus infectiosus (Faulecke) and impetigo commissural (Sabouraud). It was believed by Sabouraud, Colcott Fox, Cole and Jadassohn,2Lane,3Smith,4and others, in view of their investigative work, to be of streptococcic origin, and at the present time, although the streptococcus has not been proved to be the etiologic agent, it is almost universally regarded as such. It should be mentioned that only in rare instances has impetigo been seen in patients with perlèche, only with such frequency as might be accounted for on the grounds