THE URINARY EXCRETION OF ETRAHYDROCORTISOL, 3α-ALLOTETRAHYDROCORTISOL AND TETRAHYDROCORTISONE IN YOUNG AND ELDERLY MEN AND WOMEN*

Abstract
Tetrahydrocortisol, 3[alpha]-allotetrahydrocortisol and tetrahydrocortisone are regularly occurring metabolites in the urine of young and elderly men and women. The rate of excretion of these steroids, expressed as a function of creatinine excretion, is not altered by age or sex. The average proportions of each of these metabolites to their total excretion is approximately 30% for tetrahydrocortisol, 20% for 3[alpha]-allotetrahydrocortisol and 50% for tetrahydrocortisone.