The Relative Significance of Factors Affecting Postoperative Survival in Astrocytomas, Grades One and Two

Abstract

SUMMARY: The records of 107 patients with supratentorial astrocytomas, Grades 1 and 2, treated surgically between I960 and 1970 were analyzed. Abstracted clinical data was retrospectively analyzed with respect to the relative significance of different factors affecting survival. Twenty-eight patients were alive at the time of follow-up in 1974. Age, clinical grade at surgery and radiation therapy were the most important determinants of prolonged postoperative survival. The more malignant astrocytomas occurring in the Province of Alberta had previously been reviewed. The present study was carried out to demonstrate the relative influence of histologic grade of astrocytomas and to analyze the factors affecting postoperative survival in the low grade, supratentorial astrocytomas.