Lassa virus glycoproteins: antigenic and immunogenic properties of synthetic peptides to GP1
- 1 March 1990
- journal article
- research article
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 115 (1-2), 133-137
- https://doi.org/10.1007/bf01310630
Abstract
Synthetic peptides corresponding to predicted Lassa virus GP1 glycoprotein B-epitopes were used to study the antigenicity and immunogenicity of the protein. ELISA results showed that guinea pig polyclonal anti-Lassa virus serum bound effectively to peptides corresponding to amino acid residues 119–133 and 164–176 of the GP1 protein. Essentially it did not react to a peptide corresponding to GP1 amino acid residues 234–256. Sera obtained against peptides representing amino acid residues 119–133 and 164–176 reacted with inactivated purified Lassa virus.This publication has 14 references indexed in Scilit:
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